ThePeptideGuide.uk LogoNavigation

Educational purposes only. Not medical advice. Consult healthcare professionals before use.

Healing & Recovery
Preclinical

AHK-Cu

AHK-Cu

Also known as: Copper Peptide AHK-Cu, AHK Copper, Tripeptide Copper AHK

Overview

Key Facts

Primary Goal: Research and therapeutic applications of AHK-Cu

Binds copper(II) ions and delivers them to dermal papilla cells. Upregulates VEGF expression to enhance follicular blood supply.

Dosing Information

Half-Life

~1-2 hours

Typical Dose

0.5–2 mg

Frequency

Once daily (topical to scalp or skin)

Cycle Length

8-16 weeks continuous use for hair growth assessment

Administration Routes:
subcutaneoustopical

Benefits

  • Stimulates hair follicle proliferation (superior to minoxidil in vitro)
  • Promotes dermal papilla cell growth and vascularization
  • Supports collagen and elastin synthesis
  • Enhances wound healing and tissue repair
  • Increases follicle size and hair shaft thickness

Side Effects

Mild scalp irritation or rednessmild
Transient injection site reaction if used subcutaneouslymild
Rare copper sensitivity reactionmild

Mechanism of Action

1

Binds copper(II) ions and delivers them to dermal papilla cells

2

Upregulates VEGF expression to enhance follicular blood supply

3

Activates Wnt/beta-catenin signaling pathway in hair follicle stem cells

4

Stimulates extracellular matrix production in the dermal papilla

Contraindications

Do not use this peptide if any of the following apply:

  • Wilson's disease or copper metabolism disorders
  • Copper allergy
  • Pregnancy or breastfeeding

Storage & Reconstitution

Unreconstituted (Powder)

Temperature2–8°C (36–46°F)
DurationUp to 3 months

Reconstituted (Mixed)

Temperature2–8°C (36–46°F)
Duration2-4 weeks

Research Summary

Preclinical

Research published in the Journal of Biological Chemistry and related journals demonstrated that AHK-Cu stimulates dermal papilla cell proliferation more effectively than GHK-Cu at equivalent concentrations. A 2007 study showed that AHK-Cu increased hair follicle size and prolonged the anagen (growth) phase in organ culture models. While clinical trial data in humans remains limited, its mechanism of action through copper delivery and Wnt pathway activation makes it a promising candidate for alopecia treatment.

Frequently Asked Questions

Common questions about AHK-Cu

UK-Specific Information

Exclusive data points and guidance for UK residents using AHK-Cu

UK Lab Testing

UK Lab Testing

Recommended labs: Medichecks, Thriva (£89-£149 for peptide safety panel)

Why this matters: UK-specific lab testing guidance not available on US competitor sites

Commonly Stacked With

Share on TikTok

Generate a trackable link to share this peptide information on TikTok