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Educational purposes only. Not medical advice. Consult healthcare professionals before use.

Healing & Recovery
Preclinical

GHRP-2

GHRP-2

Also known as: Pralmorelin, KP-102, D-Ala-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2

Overview

Key Facts

Primary Goal: Research and therapeutic applications of GHRP-2

Potently agonizes the GHS-R1a receptor, producing the largest GH pulse among GHRPs. Stimulates hypothalamic GHRH neurons to amplify GH release.

Dosing Information

Half-Life

15-60 minutes

Typical Dose

100–300 mcg

Frequency

2-3 times daily

Cycle Length

8-16 weeks

Administration Routes:
subcutaneousintravenous

Benefits

  • Strongest GH release among GHRPs
  • Improved lean body mass and muscle recovery
  • Moderate appetite stimulation
  • Enhanced sleep quality
  • Potential neuroprotective effects

Side Effects

Moderate appetite increasemild
Elevated cortisol and prolactin (less than GHRP-6)mild
Water retentionmild
Possible drowsinessmild
Tingling at injection sitemild

Mechanism of Action

1

Potently agonizes the GHS-R1a receptor, producing the largest GH pulse among GHRPs

2

Stimulates hypothalamic GHRH neurons to amplify GH release

3

Moderate ghrelin-like signaling increases appetite through NPY/AgRP pathway activation

Contraindications

Do not use this peptide if any of the following apply:

  • Active cancer or tumours
  • Pregnancy or breastfeeding
  • Conditions aggravated by elevated cortisol
  • Uncontrolled diabetes

Storage & Reconstitution

Unreconstituted (Powder)

Temperature2–8°C (36–46°F) or -20°C (-4°F) for long-term
DurationUp to 3 months

Reconstituted (Mixed)

Temperature2–8°C (36–46°F)
Duration2-4 weeks

Note: Protect from light. Do not freeze reconstituted solution.

Research Summary

Preclinical

GHRP-2 (Pralmorelin) has been approved in Japan as a diagnostic agent for GH deficiency and extensively studied in clinical settings. Research demonstrates it produces the highest peak GH levels among GHRPs, approximately 20-40% greater than GHRP-6. Studies also suggest neuroprotective effects in models of neurodegeneration.

Frequently Asked Questions

Common questions about GHRP-2

UK-Specific Information

Exclusive data points and guidance for UK residents using GHRP-2

UK Lab Testing

UK Lab Testing

Recommended labs: Medichecks, Thriva (£89-£149 for peptide safety panel)

Why this matters: UK-specific lab testing guidance not available on US competitor sites

Commonly Stacked With

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