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Healing & Recovery
Preclinical
Trending on TikTok(8,000+)

TB-500

TB-500

Also known as: TB4, Thymosin Beta-4, Tβ4

Overview

Key Facts

Primary Goal: Research and therapeutic applications of TB-500

Sequesters G-actin to regulate cytoskeletal dynamics. Upregulates cell surface integrin expression for adhesion.

Dosing Information

Half-Life

~2 hours

Typical Dose

2–5 mg

Frequency

2x per week (loading), 1x per week (maintenance)

Cycle Length

4-8 weeks loading, then maintenance

Administration Routes:
subcutaneousintramuscular

Benefits

  • Promotes tissue repair and regeneration
  • Reduces inflammation and fibrosis
  • Enhances cell migration to injury sites
  • Improves flexibility and range of motion
  • Supports cardiac tissue repair
  • Promotes hair regrowth

Side Effects

Temporary lethargymild
Head rush shortly after injectionmild
Injection site rednessmild
Mild flu-like symptoms during loading phasemild

Mechanism of Action

1

Sequesters G-actin to regulate cytoskeletal dynamics

2

Upregulates cell surface integrin expression for adhesion

3

Promotes endothelial cell differentiation for angiogenesis

4

Activates matrix metalloproteinases for tissue remodeling

5

Downregulates pro-inflammatory cytokines

Contraindications

Do not use this peptide if any of the following apply:

  • Active cancer (promotes angiogenesis)
  • Pregnancy or breastfeeding
  • Active infections (theoretical immune modulation)

Storage & Reconstitution

Unreconstituted (Powder)

Temperature2–8°C (36–46°F) or -20°C (-4°F) for long-term
DurationUp to 3 months

Reconstituted (Mixed)

Temperature2–8°C (36–46°F)
Duration2-3 weeks

Research Summary

Preclinical

Thymosin Beta-4 has been studied in clinical trials for wound healing, corneal repair, and cardiac recovery post-MI. RegeneRx Biopharmaceuticals has conducted multiple Phase 2 trials. Strong preclinical evidence for musculoskeletal repair and cardiac protection.

Frequently Asked Questions

Common questions about TB-500

UK-Specific Information

Exclusive data points and guidance for UK residents using TB-500

UK Lab Testing

UK Lab Testing

Recommended labs: Medichecks, Thriva (£89-£149 for peptide safety panel)

Why this matters: UK-specific lab testing guidance not available on US competitor sites

Commonly Stacked With

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