What is the half-life of DSIP?

DSIP has a half-life of ~15 minutes (rapid enzymatic degradation), which is why it's typically administered 1x daily before bed for optimal therapeutic effect.

How do I reconstitute DSIP?

Add bacteriostatic water to the peptide vial slowly down the side. Typical reconstitution uses 2-3ml of water for a 5mg vial. Gently swirl, do not shake.

Anti-Ageing

Preclinical

DSIP

Also known as: DSIP Recovery Peptide, Delta Sleep Peptide

Overview

Key Facts

Primary Goal: A nonapeptide originally isolated from rabbit brain that promotes deep delta-wave sleep

A nonapeptide originally isolated from rabbit brain that promotes deep delta-wave sleep. Increasingly recognized for its role in recovery through improved sleep architecture, stress modulation, and hormonal regulation. Half-Life ~15 minutes (rapid enzymatic degradation) Typical Dose 100–300 mcg Frequency 1x daily before bed Cycle Length 2-4 weeks, cycling on/off

Dosing Information

Half-Life

~15 minutes (rapid enzymatic degradation)

Typical Dose

100–300 mcg

Frequency

1x daily before bed

Cycle Length

2-4 weeks, cycling on/off

Administration Routes:

subcutaneousintramuscular

Storage & Reconstitution

Unreconstituted (Powder)

Temperature2–8°C (36–46°F) or -20°C (-4°F) for long-term

DurationUp to 3 months

Reconstituted (Mixed)

Temperature2–8°C (36–46°F)

Duration1-2 weeks

Note: Protect from light. Do not freeze reconstituted solution.

Research Summary

Preclinical

Discovered in 1977 by Schoenenberger and Monnier. Studied in human trials for insomnia, chronic pain, and withdrawal syndromes with mixed but promising results. Most research from 1980s-1990s European studies. Mechanism remains complex and not fully elucidated.