What is the half-life of Ipamorelin?

Ipamorelin has a half-life of ~2 hours, which is why it's typically administered 2-3 times daily for optimal therapeutic effect.

How do I reconstitute Ipamorelin?

Add bacteriostatic water to the peptide vial slowly down the side. Typical reconstitution uses 2-3ml of water for a 5mg vial. Gently swirl, do not shake.

Growth Hormone

Phase 2

Ipamorelin

Also known as: IPA, NNC 26-0161

Overview

Key Facts

Primary Goal: A highly selective growth hormone releasing peptide (GHRP) that stimulates GH release through the ghrelin receptor without significantly affecting cortisol, prolactin, or appetite

A highly selective growth hormone releasing peptide (GHRP) that stimulates GH release through the ghrelin receptor without significantly affecting cortisol, prolactin, or appetite. Considered one of the cleanest GH secretagogues available. Half-Life ~2 hours Typical Dose 100–300 mcg Frequency 2-3 times daily Cycle Length 8-16 weeks

Dosing Information

Half-Life

~2 hours

Typical Dose

100–300 mcg

Frequency

2-3 times daily

Cycle Length

8-16 weeks

Administration Routes:

subcutaneous

Storage & Reconstitution

Unreconstituted (Powder)

Temperature2–8°C (36–46°F) or -20°C (-4°F) for long-term

DurationUp to 3 months

Reconstituted (Mixed)

Temperature2–8°C (36–46°F)

Duration2-4 weeks

Research Summary

Phase 2

Ipamorelin has been studied in multiple clinical trials including mail-operative ileus and growth hormone deficiency models. Research consistently demonstrates dose-dependent GH release with a favorable selectivity profile, showing no clinically significant increases in ACTH, cortisol, or prolactin at therapeutic doses. It is widely regarded as the most side-effect-friendly GHRP.