What is the half-life of Selank?

Selank has a half-life of ~several minutes (active metabolites persist 3-5 hours), which is why it's typically administered 1-3 times daily for optimal therapeutic effect.

How do I reconstitute Selank?

Add bacteriostatic water to the peptide vial slowly down the side. Typical reconstitution uses 2-3ml of water for a 5mg vial. Gently swirl, do not shake.

Healing & Recovery

Phase 3

Selank

Also known as: TP-7, Selanc

Overview

Key Facts

Primary Goal: A synthetic heptapeptide anxiolytic derived from the endogenous immunomodulatory peptide tuftsin (Thr-Lys-Pro-Arg) with the same Pro-Gly-Pro stabilizing extension used in Semax

A synthetic heptapeptide anxiolytic derived from the endogenous immunomodulatory peptide tuftsin (Thr-Lys-Pro-Arg) with the same Pro-Gly-Pro stabilizing extension used in Semax. Developed alongside Semax at the Institute of Molecular Genetics in Russia, Selank is approved there as an anxiolytic and nootropic with immunomodulatory properties. Half-Life ~several minutes (active metabolites persist 3-5 hours) Typical Dose 150–500 mcg Frequency 1-3 times daily Cycle Length 14-30 days

Dosing Information

Half-Life

~several minutes (active metabolites persist 3-5 hours)

Typical Dose

150–500 mcg

Frequency

1-3 times daily

Cycle Length

14-30 days

Administration Routes:

subcutaneous

Storage & Reconstitution

Unreconstituted (Powder)

Temperature2–8°C (36–46°F)

DurationUp to 3 months

Reconstituted (Mixed)

Temperature2–8°C (36–46°F)

Duration2-4 weeks

Research Summary

Phase 3

Selank was approved in Russia in 2009 for generalized anxiety disorder and as a nootropic. Clinical studies demonstrated anxiolytic efficacy comparable to medazepam (a benzodiazepine) without sedation, cognitive impairment, or withdrawal symptoms. Research has confirmed its influence on over 50 genes related to GABAergic signaling, serotonin transport, and immune function. Its dual anxiolytic-immunomodulatory profile is unique among peptide-based compounds.