What is the half-life of Thymalin?

Thymalin has a half-life of ~3-4 hours, which is why it's typically administered Once daily for 5-10 day cycles for optimal therapeutic effect.

How do I reconstitute Thymalin?

Add bacteriostatic water to the peptide vial slowly down the side. Typical reconstitution uses 2-3ml of water for a 5mg vial. Gently swirl, do not shake.

Anti-Ageing

Preclinical

Thymalin

Also known as: Thymalin bioregulator, Thymic extract peptide

Overview

Key Facts

Primary Goal: A peptide bioregulator derived from the thymus gland, developed by Russian researchers Khavinson and Morozov

A peptide bioregulator derived from the thymus gland, developed by Russian researchers Khavinson and Morozov. Thymalin restores immune function by supporting T-cell maturation and thymic activity, which naturally decline with age (thymic involution). It has been studied extensively in geriatric populations for its immune-restorative and longevity-promoting effects. Half-Life ~3-4 hours Typical Dose 5–10 mg Frequency Once daily for 5-10 day cycles Cycle Length 5-10 days on, 4-6 months off

Dosing Information

Half-Life

~3-4 hours

Typical Dose

5–10 mg

Frequency

Once daily for 5-10 day cycles

Cycle Length

5-10 days on, 4-6 months off

Administration Routes:

subcutaneousintramuscular

Storage & Reconstitution

Unreconstituted (Powder)

Temperature2–8°C (36–46°F)

DurationUp to 3 months

Reconstituted (Mixed)

Temperature2–8°C (36–46°F)

Duration2-4 weeks

Research Summary

Preclinical

In a landmark 15-year study by Khavinson and colleagues, elderly patients receiving annual courses of thymalin and epithalon showed a 28% reduction in mortality compared to controls, along with significant improvements in immune markers, endocrine function, and cardiovascular health. Thymalin has been used clinically in Russia for over 30 years in immunocompromised and geriatric patients. Western clinical trial data remains limited, but the existing body of research is substantial.