What is the half-life of Thymosin Alpha-1?

Thymosin Alpha-1 has a half-life of ~2 hours, which is why it's typically administered 2x per week for optimal therapeutic effect.

How do I reconstitute Thymosin Alpha-1?

Add bacteriostatic water to the peptide vial slowly down the side. Typical reconstitution uses 2-3ml of water for a 5mg vial. Gently swirl, do not shake.

Anti-Ageing

Approved

Thymosin Alpha-1

Also known as: Ta1, Zadaxin, Thymalfasin

Overview

Key Facts

Primary Goal: A 28-amino acid peptide originally isolated from thymic tissue by Allan Goldstein in the 1970s

A 28-amino acid peptide originally isolated from thymic tissue by Allan Goldstein in the 1970s. FDA orphan drug and approved in over 35 countries for hepatitis B/C and as an immune adjuvant. Considered the gold standard immune-modulating peptide. Half-Life ~2 hours Typical Dose 1.6–3.2 mg Frequency 2x per week Cycle Length 8-12 weeks, may be used long-term under medical supervision

Dosing Information

Half-Life

~2 hours

Typical Dose

1.6–3.2 mg

Frequency

2x per week

Cycle Length

8-12 weeks, may be used long-term under medical supervision

Administration Routes:

subcutaneous

Storage & Reconstitution

Unreconstituted (Powder)

Temperature2–8°C (36–46°F)

DurationUp to 3 months

Reconstituted (Mixed)

Temperature2–8°C (36–46°F)

Duration2-4 weeks

Research Summary

Approved

3 studies

Approved in over 35 countries for chronic hepatitis B/C and as a vaccine adjuvant. Granted FDA orphan drug designation. Extensive clinical trial data including Phase 3 studies in hepatitis and Phase 2 studies as cancer immunotherapy adjunct. SciClone Pharmaceuticals conducted large-scale RCTs demonstrating improved viral clearance and immune reconstitution.